Sucralose and gut biota

Interesting. However:

  1. The study is on mice; humans are liklely to be very different
  2. How many mice was in their cohort - does it say?
  3. There is no mention of the mice’s diet before and during the experiment. This is crucial on a number of levels, for example - diets rich in soluble fibres and prebiotics increase gut flora populations. It could be that these fibres protect the microflora. The fibre profile of the mice’s diet could be crucial.
  4. There might be other things in their diet that affect the microflora
  5. They treated mice with a pro rata in respect of weight amount of the ADI of sucralose compared to humans - does this reflect humans?
  6. How do the results of the study translate to human health? Sure, we can make assumptions.

This study is, for sure, a worthwhile read, but it should be looked at in combination with other research.

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